Systemic Lupus Erythematosus (SLE) Nephritis Classes and Prognosis




Class I has no histologic changes and has the best prognosis.
Class II has proliferation in the mesangium and has good prognosis.
Class III has focal proliferation. It has variable prognosis.
Class IV has diffuse proliferation and bad prognosis.
Class V has membranous changes and relatively better progrnosis.
Class VI has scarred glomeruli and end stage disease.


This letter M has five red circles. (Membranous)

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