Iloprost

5 day intravenous infusion Of Iloprost has been proved effective in the treatment of severe Raunaud's secondary to Scleroderma. It is also of proven efficacy in Heparin induced thrombocytopenia, Macular degeneration, Angina pectoris. However it is not FDA approved for these purposes.
FDA has approved its use only in pulmonary arterial hypertension