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CHANTIX® (varenicline) is a relatively recently introduced (Approved by FDA in May 2006) non-nicotine prescription drug to help adults (>18 yrs) in smoking cessation.
Mech of action: It competitively binds to α4β2 nicotinic ACh receptors in the brain and has agonistic as well as antagonist effects.
Adverse Effects: Some patients reported changes in behavior, agitation, depressed mood, suicidal thoughts which caused much concern to its use. Other more common S/E include nausea, vomiting, sleep problems (insomnia, bizarre dreams etc), constipation etc
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The main doses of chantix medication are 0.5mg and 1mg tablets. At the start of the treatment, you need to take the lower dose and then increase it after few weeks. The recommended dose of chantix should be swallowed as a whole with a glass of water. The treatment period with chantix medication extends to about 12 weeks. http://www.chantixhome.com/
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