Kawasaki Disease

Fever persisting at least five days*: the fever is generally high and spiking (often to 40°C [104°F] or higher).

Presence of at least four of the following features:

Changes in extremities: including redness, swelling and, sometimes, induration of the hands and feet. Desquamation of the fingers and toes occurs (Usually 2-3 weeks after fever). Beau's lines (white lines across the fingernails) may appear after 2-3 months.

Rash: may have several forms, including urticarial exanthem. Bullae and vesicles are not seen. The rash usually appears within five days after the onset of fever.

Bilateral conjunctival injection: the bulbar conjunctivae, rather than the palpebral or tarsal conjunctivae, are red. Typically, the limbic region is spared. It is not associated with an exudate and is usually painless.

Changes in the lips and oral cavity:including strawberry tongue, redness and cracking of the lips, and erythema of the oropharyngeal mucosa. No ulcers usually.

 

Cervical lymphadenopathy: the lymphadenopathy is usually unilateral, with firm and slightly tender nodes. Cervical lymphadenopathy is the least common feature found in the United States. It is a much common finding in Asia.